AIDS and Cancer Specimen Resource (ACSR) (UM1)

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In this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) is seeking applications for the AIDS and Cancer Specimen Resource (ACSR). The primary objective of the ACSR will be to acquire, store and equitably distribute tumor tissues, biological fluids and associated demographic data from patients with HIV-associated malignancies. In addition, the ACSR will serve and support biorepository banking activities for the AIDS Malignancy Clinical Trials Consortium (AMC). The AMC is an NCI funded, multicenter clinical trials group that performs clinical trials research in the treatment and prevention of HIV-associated malignancies. Due to the changing HIV epidemic and recent estimates of the associated malignancy trends, applicants are encouraged to focus their efforts in acquiring high priority collections that would include: 1) biospecimens with associated clinical, pathological, diagnostic, and demographic data; 2) fresh frozen biospecimens that are suitable for comprehensive molecular and genomic analyses; 3) biospecimens collected with informed consent acceptable for high level future use for deep sequencing and genome wide association studies; 4) biospecimens representing non-AIDS defining cancers (NADCs); and 5) biospecimens from the developing world, especially Sub-Saharan Africa.

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