Alcohol Pharmacotherapy and the Treatment and Prevention of HIV/AIDS (R01)

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Purpose. Under this Funding Opportunity Announcement (FOA), the National Institute on Alcohol Abuse and Alcoholism requests Research Project Grant (R01) applications: 1) to test innovative single and combined pharmacologic therapies for alcohol use disorders in HIV+ populations for the purpose of improving adherence to antiretroviral medications, reducing the rate of viral mutation and toxicity related to alcohol-ARV interactions, and reducing sexual risk-taking; and 2) to assess the potential usefulness of medications for alcohol use disorders in preventing secondary HIV infections in targeted high risk populations of gay men and minority women. Mechanism of Support. This FOA will utilize the R01 grant mechanism and runs in parallel with a FOA of identical scientific scope, RFA-AA-09-008, that solicits applications under the expanded R03 grant mechanism to do initial studies of the safety and feasibility of pharmacotherapies for alcohol use disorders in HIV-infected populations. Funds Available and Anticipated Number of Awards. A total of $3.0 M will be awarded and 4-6 awards are anticipated.

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