Asthma in Older Adults (R01)

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Purpose. This FOA issued by the National Institute on Aging, the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Allergy and Infectious Diseases (NIAID) encourages Research Project Grant (R01) applications that propose to study the pathophysiology, epidemiology, diagnosis, and/or management of asthma in older adults. Much of what is known about asthma in adults is based on studies in younger adult populations; however, the mechanisms underlying asthma in some older adults may differ, which may impact on diagnostic, treatment, and prevention strategies. This FOA is intended to stimulate research to address knowledge gaps and research opportunities in asthma in later life. A variety of study approaches are encouraged with this FOA including basic, translational, clinical, and epidemiological studies. Mechanism of Support. This FOA will utilize the R01 research grant mechanism and runs in parallel with FOAs of identical scientific scope, PA-10-265, that encourages applications under the R03 small research grant mechanism, and PA-10-264, that encourages applications under the R21 exploratory/developmental grant mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

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