Biology of Manual Therapies (R21)

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- The research objective of this Funding Opportunity Announcement (FOA) is to encourage the submission of high quality studies of the basic science and mechanisms of action underlying the biomechanical, immunological, endocrinological and/or neurophysiological consequences of manual therapies, such as spinal manipulation, mobilization and massage therapy.-This FOA will use the R21 (Exploratory/Developmental Research Grant) award mechanism. -Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.-Competing renewal applications will not be accepted.-Project Period and Award Levels: The total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year.-Eligible organizations: For profit organizations; Non-profit organizations; Public or private institutions, such as universities, colleges, hospitals and laboratories; Units of State government; Units of local government; Eligible institutions of the Federal government; Domestic institutions; Foreign institutions; Faith-based or community-based organizations; Units of State Tribal government; and Units of Local Tribal government. -Eligible Project Directors/Principal Investigators (PD/PIs): Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with their institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs.-Applicants may submit more than one application, provided each application is scientifically distinct.

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