Biotechnology, Biochemical, and Biomass Engineering

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The Biotechnology, Biochemical, and Biomass Engineering (BBBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes (in vivo, in vitro, and/or ex vivo) and eventually leads to the development of enabling technology and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment. Quantitative assessments of bioprocesses are considered vital to successful research projects in the BBBE program. Fundamental to many research projects in this area is the understanding of how biomolecules and cells interact in their environment, and how those molecular level interactions lead to changes in structure, function, phenotype, and/or behavior. The program encourages proposals that address emerging research areas and technologies that effectively integrate knowledge and practices from different disciplines, and effectively incorporate ongoing research into educational activities. Research projects of particular interest in BBBE include, but are not limited to: Metabolic engineering and synthetic biologyQuantitative systems biotechnologyTissue engineering and stem cell culture technologiesProtein engineering/protein designDevelopment of novel "omics" tools for biotechnology applicationsThe duration of unsolicited awards is generally one to three years. The average annual award size for the program is $100,000 for individual investigators and $200,000 for multiple investigators. Proposals requesting a substantially higher amount than this, without prior consultation with the Program Director, may be returned without review. Proposals in the areas of nanobiotechnology, fermentation, cell culture, recombinant DNA, and enzyme technology will still be accepted, given that they represent highly innovative and potentially transformative research in these areas. Proposals outside of these specific interest areas will be considered; however, the PI should contact the Program Director prior to submission to avoid the possibility of the proposal being returned without review.Additional Program Information - 1491: (e.g., Areas of Research, Research Highlights, Conferences and Workshops, Program Director Information, etc.) ---------------------------------------------------------------------------------------------------INFORMATION COMMON TO MOST CBET PROGRAMSProposals should address the novelty and/or potentially transformative nature http://www.nsf.gov/about/transformative_research/faq.jsp of the concept being proposed, compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and /or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. Proposals submitted to this program are subject to the scope of the program's description and the availability of funds. Decisions about particular proposals are often very difficult to make and factors other than reviewer comments and ratings enter into the decision. Maintaining appropriate balance among subfields, the availability of other funding, the total amount of funds available to the program, and general Foundation policies and priorities are also important decision factors. Faculty Early Career Development (CAREER) program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Please see the following URL for more information: http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=503214Proposals for Conferences, Workshops, and Supplements: Proposals involving these activities should ideally be submitted during the regular annual proposal window, but must be discussed with the Program Director before submission. Grants for Rapid Response Research (RAPID) and EArly-concept Grants for Exploratory Research (EAGER) are also considered when appropriate. Please note that proposals of these types must be discussed with the Program Director before submission. Further details are available in the Proposal and Award Policies and Procedures Guide (PAPPG) download. Unsolicited proposals received outside of the Announced Proposal Window dates will be returned without review..

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