Centers for Education and Research on Therapeutics (CERTs)( U19)

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Purpose. AHRQ seeks U19 Research Program Cooperative Agreement applications for CERTs Research Centers (RCs) that propose a body of work addressing a minimum of three of the five programmatic interest areas described in detail later within this FOA: (1) comparative effectiveness, (2) patient safety, (3) tool development, enhancement, and/or validation, (4) health care system interventions, and (5) translation of research findings into practice or policy. These interest areas represent overarching interests of AHRQ, the Food and Drug Administration (FDA), the Centers for Medicare and Medicaid Services (CMS), and other stakeholders in therapeutics research and education. The proposed work of a CERTs RC is required to fall within a Center-proposed theme that unifies 3 to 5 major projects proposed by the RC to be conducted over the 5 year period of the grant; project partnerships with individuals and/or organizations engaged in relevant aspects of clinical care or its financing are highly encouraged. Applicants must also propose a core infrastructure that will support not only their proposed work, but also allow the future development and conduct of additional projects and activities with other funding sources and partners. Each applicant must also nominate two or more concept briefs that outline important and common issues in therapeutics that could be addressed by the applicant along with other CERTs RCs. Common issues may include, but are not limited to, methodologies, quality use of therapeutics, policies pertaining to research and education in therapeutics, development of meaningful partnerships with outside entities, or dissemination and implementation of CERTs findings. These concept briefs will inform the development of committees and working groups across the CERTs to address issues of common interest; they may also form the basis of one or more major collaborative CERTs projects or activities undertaken annually with assistance of the CERTs Scientific Forum (www.certs.hhs.gov).

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