Childhood Cancer Survivor Study (CCSS)(Limited Competition U24)

archived

The purpose of this Funding Opportunity Announcement (FOA) is to continue support for Childhood Cancer Survivor Study (CCSS) as a resource enabling broad studies on the long-term effects of cancer and its associated therapies on survivors of pediatric cancers. CCSS (originally funded as an investigator initiated program) serves the overall goal to quantify and better understand the effects of pediatric cancer and its treatment on later health of cancer survivors, including behavioral and sociodemographic outcomes. For these goals, CCSS has been designed as a comprehensive multicenter effort to comprehensively manage large cohorts of survivors of childhood cancer. The original cohort of study participants included 14,370 pediatric cancer survivors diagnosed between 1970 and 1986 as well as 3,737 siblings. Enrollment of a second cohort of survivors consisting of a similar number of subjects diagnosed between 1987 and 1999 is expected to be completed by the end of the current award period. The current CCSS structure includes 27 institutions, mostly in the U.S. but also in Canada.

High