Creating Asthma Empowerment Collaborations to Reduce Childhood Asthma Disparities (U34)

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The purpose of this FOA is to support investigators planning a clinical trial to evaluate Asthma Care Implementation Programs (ACIP) for chidren at high risk of poor asthma outcomes. Investigators must propose an ACIP for this population that translates research into community practice by integrating interventions with demonstrated efficacy from multiple sectors into a comprehensive program. Each proposed evidence-based intervention within the ACIP must address at least one of the following different sectors that can contribute to a system of care for children: medical care, family, home, and community. During the project period, investigators will conduct a community needs assessment to ensure their proposed ACIP will meet the needs of children at high risk of poor asthma outcomes within their community in the U.S. Therefore, the proposed interventions may be modified based on the community needs assessment. As the interventions included in the ACIP are modified during the U34, the proposed clinical trial to evaluate the ACIP should also be adjusted and developed into a complete protocol. On the basis of the refined interventions from each of the requisite sectors, investigators must also solidify existing relationships or engage appropriate collaborators from each of the sectors who are able to identify resources they can commit to provide for the ACIP. By the conclusion of the U34, applicants should be prepared to apply for a U01 grant, described in RFA-HL-17-001, which will support the clinical trial, assessment of the sustainability of the interventions, and define best practices for implementation of interventions in children at high risk of poor asthma outcomes.

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