Critical Illness and Injury in Aging (R01)

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Purpose. This FOA encourages Research Project Grant (R01) applications proposing to study mechanisms and management of critical illness and injury, including trauma and neurotrauma, in aging. Studies may be mechanistic, observational, or interventional in nature. Secondary analyses of existing datasets, such as from large observational studies or clinical trials, may be proposed. Animal studies are appropriate in cases where human studies are not feasible. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) grant mechanism and runs in parallel with a FOA of identical scientific scope, PA-10-044, that encourages applications under the R21 Exploratory/Developmental grant mechanism, PA-10-043, that encourages applications under the R03 Small Research grant mechanism. This FOA also runs in parallel with an FOA of similar scientific scope, PA-10-045, which encourages applications under the R34 clinical trial planning grant mechanism. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

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