Determinants and Consequences of Personalized Health Care and Prevention (U01)

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This Funding Opportunity Announcement (FOA) solicits U01 applications for economic research on the determinants and consequences of personalization in health care and prevention. The objective of the research program is to support foundational research on economic aspects of individualized health interventions that will provide a framework for subsequent applied analyses. Program Director(s)/Principal investigator(s) for projects funded under this FOA are required to participate in a Steering Committee that will help identify key strategies to support critical research advances in this field. Research to be supported by this FOA includes analyses and development of research tools to advance understanding of: factors that affect the value of personalized interventions to individuals and their families, health care providers and payers, and society at large; incentives and constraints facing individuals and their families, health care providers, research organizations, drug and device manufacturers, and others and how they affect the actual and optimal extent to which interventions are tailored to patients personal characteristics or preferences; and strategies to promote improvements in health and cost outcomes through personalization of health care and preventive interventions. The purpose of this FOA is to expand generalizable understanding of the determinants and consequences of personalization in health care and prevention; it is not primarily intended to support evaluation of specific interventions or strategies for addressing particular health conditions.

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