Development of Multifunctional Drug and Gene Delivery Systems (R01)

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Purpose. This Funding Opportunity Announcement (FOA), issued by the National Institute of Biomedical Imaging and Bioengineering and the National Heart, Lung, and Blood Institute, National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose the engineering of novel, multifunctional drug and gene delivery systems that can target therapies to particular cells and intracellular compartments and can monitor delivery and determine therapeutic efficacy through the integration of advanced imaging and/or sensing technologies into the delivery system. Applications should propose to develop at least one prototype system by the end of the project period. Applications that are submitted to this FOA should include investigators from both the drug/gene delivery and imaging fields. Applicants are strongly encouraged to use the Multi-PD/PI model to meet the imaging and drug/gene delivery expertise. Mechanism of Support. This FOA utilizes the NIH R01 research grant award mechanism. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received.

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