Developmental Projects in Complementary Approaches to Cancer Care and Treatment (R21)

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Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), and the National Institute of Nursing Research (NINR), of the National Institutes of Health, invites applications for basic, pre-clinical, and clinical complementary cancer research. The research should relate to the areas of prevention, diagnosis, and treatment of cancer as well as management of cancer symptoms and side effects due to conventional cancer treatment. In addition, this FOA encourages the development and application of emerging and innovative technologies, including identification of novel therapeutics in the pharmacopoeia of Traditional Medical Systems (as defined by the World Health Organization), use of complementary approaches to improve the therapeutic ratio of standard and investigational anti-cancer therapies, and research on lifestyle modifications (e.g. diet, exercise, mind-body approaches) for their impact on cancer outcomes (e.g., response to conventional cancer therapy, survival). The overarching goals of this FOA is to encourage investigators to submit high quality, preliminary research of humans that will advance the science of Complementary and Alternative Medicine (CAM) and provide a solid foundation and justification for future research project (R01) grant applications to definitively determine the efficacy of CAM approaches. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, PA-09-168, that encourages applications under the NIH Small Research Grant (R03) award mechanism

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