Dietary Supplement Research Centers: Botanicals (P50)

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Purpose. ODS, NCCAM and NCI invite new and renewal applications to support research centers which will (1) promote collaborative integrated interdisciplinary study of botanicals, particularly those found as ingredients in dietary supplements and (2) conduct research of high potential for being translated into practical benefits for human health. This initiative is intended to advance the spectrum of botanical research activities, ranging from plant identification and characterization to early phase clinical studies. Preclinical research that will inform future clinical studies is encouraged as the primary research focus of this program. ODS has a particular interest in botanicals as part of health care for conditions relating to health maintenance or primary prevention. NCCAM is interested in the study of botanicals broadly used by the American public. The NCI Division of Cancer Prevention is interested in supporting research focused on mechanisms by which botanically derived bioactive food components might influence cancer risk and tumor behavior. This FOA is not supportive of applications focused on new drug discovery. Only investigators who submitted a pre-application in response to RFA-OD-09-002 and were notified are eligible to submit full applications under this FOA.

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