DoD Duchenne Muscular Dystrophy, Career Development Award

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The DMDRP Career Development Award mechanism supports early-career investigators in conducting impactful Duchenne research under the mentorship of an experienced muscular dystrophy researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of Duchenne research. Applicants should also demonstrate that the proposed research has high potential to lead to or make breakthroughs in Duchenne. Preliminary data are required. Key elements of this award are as follows: • Principal Investigator (PI): The PI must be an independent, early-career research- or physician-scientist and at minimum 2 years post completion of his/her PhD, MD, or equivalent terminal degree (excluding time spent in residency or on family medical leave). The PI’s record of accomplishments and the proposed research will be evaluated regarding his/her potential for contributing to the field of Duchenne research. • Mentorship: The Mentor must be an experienced muscular dystrophy researcher as demonstrated by a strong record of funding and publications in muscular dystrophy research. The Mentor must hold a position at or above the level of an Associate Professor (or equivalent). In addition, the Mentor must demonstrate a commitment to developing the PI’s career in Duchenne research. • Career Development: A Career Development Plan is required and should be prepared with appropriate guidance from the Mentor. A clearly articulated strategy for acquiring the necessary skills, competence, and expertise to establish a career at the forefront of Duchenne research should be included. The plan should outline how the PI will gain experience in Duchenne research. Because career development is the focus of this award, the PI’s institution must demonstrate a commitment to the PI through a minimum of 30% protected time for Duchenne research, though more protected time is highly desirable. • Impact: The proposed research should have high potential impact to improve the function and quality of life, and to extend the life span of all individuals with Duchenne. The anticipated direct costs budgeted for the entire period of performance for an FY17 DMDRP Career Development Award will not exceed $275,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

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