DoD Neurofibromatosis Investigator-Initiated Research Award

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The NFRP Investigator-Initiated Research Award mechanism was first offered in FY96. Since then, 341 Investigator-Initiated Research Award applications have been received, and 96 have been recommended for funding. The NFRP Investigator-Initiated Research Award supports basic and clinically oriented research that will: � Provide insight into the development of NF and Schwannomatosis, � Result in substantial improvements over today�s approach to the diagnosis and treatment of NF and/or Schwannomatosis, and � Have an impact on the quality of life of persons with those diseases. DOD FY11 NFRP Investigator-Initiated Research Award 4 Areas of Encouragement: The FY11 NFRP encourages research applications that specifically address the critical needs of the NF community in the following areas: � Complications of NF with high mortality such as neoplasms and cerebrovascular abnormalities; � Complications of NF with high morbidity such as skeletal maladies, learning deficits, hormone-associated effects, and pain; � Refinement and standardization of imaging techniques, molecular and cellular markers, and quality of life metrics for use in future clinical trials; and � Translational research such as the development or preclinical testing of therapeutic agents for the treatment of NF. Applications must include preliminary data that is relevant to NF and/or Schwannomatosis and the proposed project. Optional Qualified Collaborator: The FY11 NFRP strongly supports collaborative research between basic scientists and clinical researchers, and between academic scientists and biotechnology/pharmaceutical industry scientists. Collaborations that bring new perspectives from other disciplines, or bring new investigators into the NF field are also strongly encouraged.

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