DoD Neurofibromatosis New Investigator Award

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The NFRP New Investigator Award (NIA) mechanism was first offered in FY99. Since that time, 179 NIA applications have been received, and 38 have been recommended for funding. The intent of the NFRP NIA is to support the career transition and/or continued development of promising independent investigators in the field of neurofibromatosis research. Experience in NF research is allowed, but not required. However, Principal Investigators (PIs) with a limited background in NF research are strongly encouraged to have a collaborator who is experienced in the NF field. NIA proposals must include preliminary data originating from the PI, research team, or collaborator that is relevant to NF and the proposed project. Areas of Encouragement: The FY10 NFRP encourages research proposals that specifically address the critical needs of the NF community in the following areas: • Complications of NF with high mortality such as neoplasms and cerebrovascular abnormalities; DOD FY10 Neurofibromatosis New Investigator Award 3 • Complications of NF with high morbidity such as skeletal maladies, learning deficits, hormone-associated effects, and pain; • Refinement and standardization of imaging techniques, molecular and cellular markers, and quality of life metrics for use in future clinical trials; and • Translational research such as the development or preclinical testing of therapeutic agents for the treatment of NF. Research involving human subject use is permitted; however, clinical trials are NOT ALLOWED under this funding opportunity. In general, a clinical trial is defined as a prospective study where an intervention (e.g., device, drug, behavioral, surgical procedure, or other) is tested on human subjects for a measurable outcome. PIs wishing to apply for funding for a clinical trial should utilize the FY10 NFRP Clinical Trial Award mechanism. Refer to the General Application Instructions, Appendix 5, for additional information about studies involving human subjects, human subjects data, or human anatomical substances.

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