DoD Peer Reviewed Cancer Collaborative Translational Science Award

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The key initiative of the Collaborative Translational Science Award is to encouragecollaborations among clinicians and laboratory scientists that accelerate the movement ofpromising ideas in melanoma and other skin cancers into clinical applications. This award isintended to support both new and established scientists across a broad spectrum of disciplines inresearch projects that are likely to make a major impact on melanoma and other skin cancers forthose service members (and their families) deployed in areas of high exposure. No other topicareas will be allowed.The FY09 PRCRP Collaborative Translational Science Award requests applications fromthese Focus Areas only:Research into melanoma and other skin cancers related to deployments of service members toareas of high exposure by: Understanding molecular and immunological effects of UV at the level of the cell andat the level of the human host. The genetic epidemiology and increased susceptibility to melanoma and other skincancers.DOD Peer Reviewed Cancer Research Program Collaborative Translational Science Award 3Applications to the FY09 PRCRP Collaborative Translational Science Award will be rated ontheir responsiveness to these Focus Areas. It is the responsibility of the applicant to clearlyand explicitly articulate the project’s military relevance.The Collaborative Translational Research Award supports the development of translationalresearch collaborations among two or three independent investigators (known as partners) toaddress one of the Focus Areas in melanoma and other skin cancers in a manner relevant tomilitary service that would be less readily achievable through separate efforts. At least onepartner must have experience either in melanoma/other skin cancer research or inmelanoma/other skin cancer patient care. It should be clear that all partners have equalintellectual input into the design of the research project. A proposed project in which one of thepartners merely supplies tissue samples or access to patients will not meet the intent of thismechanism.Observations that drive a research idea may be derived from a laboratory discovery, populationbasedstudies, or a clinician’s firsthand knowledge of patients and anecdotal data. The ultimategoal of translational research is to move an observation forward into the clinical application. TheCollaborative Translational Science Award supports preclinical studies in animal models andhuman subjects and human anatomical substances, correlative studies that are associated with anexisting clinical trial, and projects that develop clinical endpoints for clinical trials. Developingthe research plan must involve a reciprocal flow of ideas and information within the researchteam (from bench to bedside, and from bedside to bench).

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