DoD Tuberous Sclerosis Complex Exploration – Hypothesis Development Award

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The TSCRP Exploration – Hypothesis Development Award (EHDA) mechanism was first offered in FY09. Since that time, 24 EHDA applications have been received, and 4 have been recommended for funding. The EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in tuberous sclerosis complex research. Results of studies conducted through this award should provide the scientific rationale upon which a new hypothesis can be based, or these results should provide initial principles of an innovative hypothesis. This award is designed to provide investigators with the opportunity to pursue serendipitous observations. The presentation of preliminary data is encouraged, but not required. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate the project’s innovation and the potential impact on TSC. Because these awards are designed for preliminary investigations, projects involving human subjects or specimens will not be supported unless they are exempt under 32 CFR 219.101(b) or eligible for expedited review (32 CFR 219.110 or 21 CFR 56.110). Additional information on the protection of human subjects and exempt or expedited review status may be found at https://www.bids.tswg.gov/TSWG/bids.nsf/5DD5E2BA50F02C18852572B1005F5B8B/$file/Title_32_CFR_Part_219.pdf. Applications proposing studies that do not qualify for exempt or expedited review status will be administratively withdrawn. PIs wishing

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