DoD Tuberous Sclerosis Complex Idea Development Award

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The TSCRP Idea Development Award mechanism was first offered in FY02. Since then, 230 Idea Development Award applications have been received, and 45 have been recommended for funding.The FY14 TSCRP Idea Development Award promotes new ideas that are in the early stages of development and have the potential to yield high-impact findings and new avenues of investigation. This award mechanism supports conceptually innovative, high-risk/potentially high-reward research that could ultimately lead to critical discoveries in TSC research and/or improvements in patient care. Research projects should include a well-formulated, testable hypothesis based on strong scientific rationale.The following are important aspects of the Idea Development Award:1. Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities that may include high-risk/potentially high-gain approaches to TSC research. Research that is merely an incremental advance (the next logical step) is not considered innovative.2. Impact: Applications should articulate both the short- and long-term impact of the proposed research. High-impact research will, if successful, significantly advance TSC research and/or patient care.3. Preliminary Data: Preliminary data, unpublished results from the laboratory of the Principal Investigator (PI) or collaborators named on this application, and/or data from the published literature that are relevant to TSC and the proposed research project should be included.Research involving human subjects and human anatomical substances is permitted; however, clinical trials are not allowed under this funding opportunity. For more information on clinical trials and clinical research overall, a Human Subject Resource Document is provided on the Congressionally Directed Medical Research Programs (CDMRP) electronic Biomedical Research Application Portal (eBRAP) system at https://ebrap.org/eBRAP/public/Program.htm. PIs wishing to apply for funding for a clinical trial should utilize the FY14 TSCRP Pilot Clinical Trial Award mechanism (Funding Opportunity Number: W81XWH-14-TSCRP-PCTA).

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