DOD, Tuberous Sclerosis Complex Research Program, Clinical Translational Research Award

archived

The Clinical Translational Research Award supports studies that will move promising, well-founded preclinical and/or clinical research findings closer to clinical application, including diagnosis, prognosis, or treatment of TSC. Projects supported by this award mechanism may include, but not limited to: -Studies moving from preclinical to clinical research and/or the reverse, analyzing human anatomical substances and/or data associated with completed clinical trials (such as correlative studies that investigate the correlation of a set of genetic and/or environmental factors with disease progression, or the effect of an intervention on the disease outcomes, etc.) -Studies advancing clinical trial readiness through development of biomarkers, clinical endpoints, and validation of pharmacokinetics/pharmacodynamics -Pilot clinical trials where limited clinical testing (e.g., small sample size) of a novel intervention is necessary to inform the next step in the continuum of translational research.

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