Epidemiology of Lupus: Longitudinal Studies in Population-Based Cohorts

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The primary purpose of this opportunity is to fund applicants with existing access to adult lupus patient populations and can extend current knowledge over 12-17 years from baseline.  A second component of this funding opportunity will focus on the pediatric lupus - to advance existing knowledge of lupus in pediatric populations using an existing cohort of lupus patients. Because lupus is a rare condition, it is efficient to obtain new information from existing relevant cohorts with lupus.  The research objectives among both adult and pediatric populations are to: Examine the treatment (e.g., medications including opioid; type; appropriateness; etc.) of people with lupus. Determine health care access and gaps that people with lupus experience in addressing their varied health problems (e.g., general health problems as well as those for specific lupus outcomes, such as nephritis; transitions to adulthood). Determine longer term natural history (severity, chronic pain, progression, morbidity, mortality, disability and quality of life, work/ school/activity interference, etc.) of people with lupus, including assessing potential genetic factors. Examine other factors related to disparities in lupus outcomes (e.g., age, sex, and race/ethnic group). Examine lupus comorbidities.

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