Etiology, Prevention, and Treatment of Hepatocellular Carcinoma(R21)

archived

-Purpose. With this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) encourage grant applications that: (a) address the etiology and etiologic mechanisms of hepatocellular carcinoma (HCC); (b) propose development of animal models for HCC; (c) propose novel approaches to prevent HCC malignancy; (d) propose therapeutic or diagnostic tools for reliable prognostic indicators for HCC; and/or (e) develop therapeutic approaches to minimize morbidity and mortality associated with HCC in humans. The primary focus of the proposed project must be on the basic biology, prevention, and/or treatment of liver cancer. Applications solely concerned with population studies and epidemiology will not be supported in connection with this FOA. -Mechanism of Support. This FOA will utilize the R21 grant mechanism and runs in parallel with two FOAs of similar scientific scope: (1) PA-08-243, for research projects using the R01 mechanism; and (2) PAR-08-245, for program project grants under the P01 mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications; therefore, the anticipated number of awards is not known

High