Exploration of the Roles of Brown and Beige Adipose Tissue in Humans (R01)

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This Funding Opportunity Announcement (FOA) invites applications for Research Project Grants (R01) to investigate the biological functions of brown and beige adipose tissue in humans, other than heat production and maintenance of body temperature, and to explore their impact on human health. Specifically, it seeks to 1) identify physiologic or pathophysiologic conditions other than prolonged cold exposure under which browning of human subcutaneous or other white adipose depots occurs, or where the brown adipose tissue depot found in the neck region is expanded through browning; 2) test potential non-biopsy biomarkers of human subcutaneous beige fat and 3) explore the biological functions of human brown and beige fat.

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