FY09 DOD Lung Cancer Research Program Collaborative Translational Research Award

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The LCRP Collaborative Translational Research Award (CTRA) supports partnerships between clinicians and laboratory scientists at multiple institutions to conduct translational research in lung cancer.The purpose of the CTRA is to support multi-institutional, multi-disciplinary collaborations among clinicians and laboratory scientists that will accelerate the movement of promising ideas in lung cancer into clinical applications.The FY09 LCRP CTRA ONLY accepts applications that address at least two of the seven Areas of Emphasis listed below.• Identification or development of non-invasive or minimally invasive tools to improve the detection of the initial stages of lung cancer• Identification and development of tools for screening or early detection of lung cancer. Screening may include, but is not limited to, computed tomography scans, X-rays, other imaging, biomarkers, genetics/genomics/proteomics, and assessment of risk factors• Understanding the molecular mechanisms that lead to clinically significant lung cancer• Identification of the mechanisms that lead to the development of the various types of lung cancer• Identification of innovative strategies for prevention and treatment of early lung cancer• Understanding predictive and prognostic markers to identify responders and non-responders• Understanding acquired resistance to treatmentThe CTRA supports the development of translational research collaborations among four independent investigators (known as partners). The four partners, consisting of an Initiating Principal Investigator (PI) and three Partnering PIs, must be from at least two distinct institutions. The proposed research must address two or more of the seven Areas of Emphasis in a manner that would maximize the collective expertise of the investigators involved. At least one partner must be a clinician, and at least two partners must have experience either in lung cancer research or lung cancer patient care. It should be clear that all partners have equal intellectual input into the design of the research project. A proposed project in which one of the partners merely supplies tissue samples or access to patients will not meet the intent of this mechanism. See the Program Announcement for the full Funding Opportunity Description.

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