Genetic and Genomic Analysis of Xenopus (R03)

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Purpose. This funding opportunity announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Dental and Craniofacial Research (NIDCR), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Mental Health (NIMH) and the Trans-NIH Xenopus Working Group (TXWG) solicits investigator-initiated applications designed to exploit and enhance the power of Xenopus as a vertebrate model for biomedical research. Applications are welcome proposing to develop new tools or genetic or genomic resources of high priority to the Xenopus research community to advance the detection and characterization of genes, pathways, and phenotypes of interest in development, organogenesis, and in cell biological processes such as cell division, signaling and migration. In addition, applications will be welcomed that utilize recently developed genetic and genomic tools or resources to advance these same goals particularly when these projects employ tools that have not previously been made use of in Xenopus research. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources. Mechanism of Support. This FOA will utilize the NIH Small Research Grant (R03) award mechanism and runs in parallel with FOAs of identical scientific scope, [PAR-09-241] and [PAR-09-240], that solicit applications under the NIH Exploratory/Developmental (R21) and NIH Research Project Grant (R01) mechanisms, respectively.

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