Genetic and Genomic Analysis of Xenopus (R21)

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Purpose. This funding opportunity announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development solicits investigator-initiated applications designed to exploit the power of Xenopus as a vertebrate model for biomedical research. Applications are welcome proposing to develop new tools or genetic or genomic resources of high priority to the Xenopus research community to advance the detection and characterization of genes, pathways, and phenotypes of interest in development, organogenesis, and in cell biological processes such as cell division, signaling and migration. In addition, applications will be welcomed that in Xenopus utilize recently developed genetic and genomic tools or resources to advance these same goals particularly when these projects employ tools that have not previously been made use of in Xenopus research. Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism. For example, long-term projects, or projects designed to increase knowledge in a well-established area, will not be considered for R21 awards. Applications submitted under this mechanism should be exploratory and novel. These studies should break new ground or extend previous discoveries toward new directions or applications. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with FOAs of identical scientific scope, NIH Research Project Grant (R01) [PAR-09-240]and NIH Small Research Grant (R03) [PAR-09-242] mechanisms.

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