Genomic Underpinnings of Response to Rehabilitation Interventions (R01)

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This Funding Opportunity Announcement (FOA) seeks research to enhance the understanding of the role of genomic variants and mechanisms in the response to rehabilitation interventions aimed at maintaining, improving, or restoring functional abilities (e.g., activities of daily living) and quality of life in individuals with functional impairments or disabilities resulting from injury, aging, or chronic illness. This research may be carried out by 1) elucidating genomic variants or mechanisms associated with outcomes in individuals receiving rehabilitation interventions, or 2) developing and testing genomics-based rehabilitation interventions, including interventions that promote symptom or self-management as part of a strategy to achieve improved functional abilities. Interdisciplinary collaborations that include nurse scientists in the project team are strongly encouraged. Additionally, applicants should consider engaging the resources and expertise of nearby or otherwise available Clinical and Translational Science Award grant sites (CTSAs) and/or federally funded research centers where possible.

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