Human Pluripotent Stem Cell (hPSC) Research Using Non-Embryonic Sources (R01)

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-Purpose. This Agency-wide Funding Opportunity Announcement (FOA) is a Program Announcement (PA) to encourage new research applications proposing research on hPSCs from non-embryonic sources. This FOA addresses Executive Order 13435 issued by President George W. Bush on June 20, 2007. The Executive Order requires that The Secretary of Health and Human Services shall conduct and support research on the isolation, derivation, production, and testing of stem cells that are capable of producing all or almost all of the cell types of the developing body and may result in improved understanding of or treatments for diseases and other adverse health conditions, but are derived without creating a human embryo for research purposes or destroying, discarding, or subjecting to harm a human embryo. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism and runs in parallel with an FOA of identical scientific scope, PA-08-044, that encourages applications under the NIH Exploratory/Developmental (R21) grant award mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

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