Hyperpolarized NMR made simple

ended

Nuclear magnetic resonance (NMR) is one of the most powerful analytical techniques currently available, with applications ranging from synthetic chemistry to clinical diagnosis. Despite the progress in developing new systems, applications are often limited by the low sensitivity of NMR. Hyperpolarization techniques have the potential to overcome this limitation and revolutionize the use of compact NMR. However, the state-of-art devices for hyperpolarization are limited by either the need for cryogenic cooling, long setup and polarization times with the risk of experimental failure, costly systems, cumbersome equipment, and a limited range of polarizable molecules. MAGSENSE project significantly simplifies the existing Hyperpolarized NMR paradigm. Our unique approach is to produce spin order in standard hydrogen molecules to act as polarization batteries. The NMR sample with the enhanced target molecules is placed in a standard NMR spectrometer for ultrasensitive analysis. No modifications are required to the customer’s existing NMR instrumentation. MAGSENSE provides significant advantages in signal enhancement and measurement times, enabling the analysis of intermediate steps in the chemical reaction. MAGSENSE will provide many new opportunities for the fields of Synthetic chemistry, Analytical chemistry, and NMR research. It will be a market-creating innovation with Point-of-service applications, such as diagnosis in ICU units. The project will create opportunities for young researchers in the NMR field through our engagement with Universities and Technology institutes. At the same time, interested industry players have shown their support for the project. NVision is backed by leading deep-tech VC funds from the US and Europe and currently employs more than 25 physicists, engineers, and material scientists. Including professionals with more than 10 years of experience in NMR research, technology development, and project management.