Immune Defense Mechanisms at the Mucosa Cooperative Study Group (U01)

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Purpose. The National Institute of Allergy and Infectious Diseases (NIAID) invites applications from institutions/organizations to participate in a cooperative study group focused on immune defense mechanisms and immune regulation at mucosal surfaces including respiratory, gastrointestinal and urogenital tract mucosa. The goal is to break new ground in the understanding of basic mucosal immune defense mechanisms by introducing new ideas, approaches and technologies that address the difficult questions remaining in mucosal immune defense. The knowledge gained would facilitate future development of vaccines and immunotherapies to protect mucosal surfaces from infection and related immunopathologies. The cooperative study group will be composed of a set of cooperative agreement grants governed by a Steering Committee, and will draw upon an Infrastructure and Opportunities Fund to support a range of innovative, collaborative, and pilot/feasibility projects. NIAID encourages submissions from established and new investigators; applicants without a prior track record of funding in mucosal immunity are welcome to apply. Mechanism of Support. This FOA will utilize the cooperative agreement (U01) award mechanism. Funds Available and Anticipated Number of Awards. For this funding opportunity, budgets up to $250,000 direct costs per year and time periods up to five years may be requested. NIAID expects to allocate approximately $4 million in total costs in FY 2011 to fund seven to nine awards.

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