Implicating Noncoding RNAs in the Genetics of Mental Disorders (R21)

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-Purpose. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications that investigate the role of microRNAs and other noncoding RNAs in the etiology of mental disorders. The data generated by this effort will contribute to the disaggregation of the molecular machinery underlying mental disorders by integrating sequence specific modulators of post-transcriptional gene expression into a theoretical framework of disease pathophysiology, with the aim of rapid, widespread sharing of the resulting data to accelerate genetic analysis of human diseases.. -Mechanism of Support. This FOA will utilize the NIH Exploratory/Developmental (R21) award mechanism and runs in parallel with FOAs of identical scientific scope, PA-07-370, which solicits applications under the R01 mechanism and PA-07-371, which solicits applications under the Collaborative R01 mechanism. -Budget and Project Period. The total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year. The R21 is not renewable.

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