Innovative Approaches for TB Prevention and Case Finding to END TB

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The purpose of this NOFO is to develop, implement, and evaluate evidence-based and innovative approaches under the following two thematic components: Component A - Prevent TB infection and halt progression of TB disease in high-burden settings – with a focus on the following two strategies: TB preventive treatment (TPT) and nutrition; and Component B - Find TB infection and TB disease, including sub-clinical TB, using newer tools and products - in all populations including those at increased/higher risk for TB (i.e., PLHIV, children, displaced persons, healthcare workers, economically disadvantaged persons with other co-morbid conditions [alcohol use disorders, diabetes mellitus, persons who use illicit substances, undernourished], and older adults).