Integrated Preclinical/Clinical Program for HIV Topical Microbicides (IPCP-HTM) Competitive Revisions (U19)

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Purpose. The purpose of this Funding Opportunity Announcement (FOA) is to notify NIAID Integrated Preclinical/Clinical Program for HIV Topical Microbicides (IPCP-HTM) U19 grantees of the opportunity to expand the scope of their current IPCP-HTM award. The IPCP-HTM program supports multi-project, multi-disciplinary preclinical and exploratory clinical studies to advance safe, effective and acceptable novel topical microbicides and microbicide combination strategies for the prevention of HIV. Competitive revisions may be used to address gaps or opportunities in funded IPCP-HTM programs. Applicants propose to expand the scope of a current IPCP-HTM award Mechanism of Support. This Competitive Revision FOA will utilize the multi-project Cooperative Agreement (U19) award mechanism. A FOA of identical scientific scope, RFA-AI-10-006, for new IPCP-HTM awards is being published closely with this FOA. Funds Available and Anticipated Number of Awards. NIAID and NIMH anticipate making awards for a total of $6 million in FY 2011 for the combination of the Competitive Revision IPCP-HTM applications under this FOA and applications to RFA-AI-10-006, IPCP-HTM FOA. At least 1 award is anticipated.

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