Investigational Nutrigenetic Studies for Cancer Prevention (R01)

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-Purpose. This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), the National Institute of Nursing Research (NINR), and the Office of Dietary Supplements (ODS), all of the National Institutes of Health (NIH), solicits applications for research projects that can combine information on individual genetic variations from the Human Genome and International HapMap Projects to stimulate small pilot dietary intervention studies. The overarching goal is to examine whether genetic variants can predict individual response to dietary components that alter cancer processes and modify individual susceptibly to cancer. These studies will allow for personalization of cancer preventive dietary strategies to reduce cancer risk in genetically susceptible individuals. Associational and non-interventional epidemiologic-focused studies will not be supported in conjunction with this FOA.  -Mechanism of Support. This FOA uses the NIH Research Project R01 Grant mechanism and runs in parallel with an FOA of identical scientific scope, PA-08-221, that solicits applications under the NIH Exploratory/Developmental (R21) Grant mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

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