Johnston County Osteoarthritis Project: Arthritis, Disability, and Other Chronic Diseases

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Arthritis affects 52.5 million adults and is the most common cause of disability in the United States, yet it is relatively understudied given its large burden, especially in the African American population. Osteoarthritis of the hip and knee are the most common causes of arthritis disability. As OA continues to grow in prevalence and burden, much more remains to be learned from a public health perspective about its incidence, prevalence, progression, and the factors associated with each. This need has been described in documents such as the 1999 National Arthritis Action Plan - A Public Health Strategy, and is a priority for the CDC Arthritis Program. The need is also documented in the recommendations of the 2010 National Public Health Agenda for Osteoarthritis.The purpose of this funding opportunity announcement is to support a population-based longitudinal study, which is designed to: (1) refine population-based estimates of the prevalence, incidence, and progression of hip and knee osteoarthritis and related outcomes; (2) gather information on and investigate possible factors (both risk and protective, including other chronic conditions) associated with the above outcomes; and (3) determine racial or ethnic differences in outcomes and in the role of comorbid conditions and the effect of risk factors upon osteoarthritis outcomes.

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