Longitudinal Assessment of Post-traumatic Syndromes (U01)

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This Funding Opportunity Announcement (FOA) encourages cooperative research project grant (U01) applications for a multi-site, longitudinal research platform to 1) characterize post-traumatic trajectories based on dimensions of observable behavior, neurobiological changes, and other measures that may serve as markers of risk (e.g., neural network functional connectivity, cognitive functioning, emotion regulation, biomarkers of immune response) among adult trauma patients initially seen in emergency rooms and other acute trauma settings, 2) examine processes or mechanisms whereby post-trauma mental illness develops and is maintained, 3) develop algorithms to be used in the acute post-trauma time period to predict different trajectories, and 4) develop/refine measures of promising targets for future prevention and early treatment studies.

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