Mucosal Environment and HIV Prevention (MEHP) (R01)

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The National Institute of Allergy and Infectious Diseases (NIAID) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, encourages grant applications from institutions/organizations that address the goals and objectives of this funding opportunity announcement (FOA). The Mucosal Environment and HIV Prevention (MEHP) FOA is intended to support innovative proof-of-concept/feasibility non-vaccine biomedical prevention (nBP) research needed to support and advance the development of safer and more effective microbicides, Pre-Exposure Prophylaxis (PrEP), and Multipurpose Prevention Technologies (MPT). It will achieve this by supporting a better understanding of prevention candidates and strategy interaction with the micro- and macro-environments of the genital (male and female) and gastrointestinal (GI) mucosa. The MEHP FOA addresses the following 3 underserved emerging areas of Program interest: role of the microbiome in transmission/acquisition of HIV and candidate safety and efficacy, tissue responses to prevention agents, and the effect of genital secretions and hormones on susceptibility to HIV infection:

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