New Technologies for Liver Disease STTR (R41/R42)

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Purpose. The purpose of this Funding Opportunity Announcement (FOA) is to solicit Small Business Innovation Research (STTR) grant applications from small business concerns (SBCs) that propose to develop resources, research tools, instrumentations, biomarkers, devices, drugs or new and innovative approaches to diagnosis, monitoring, management, treatment and prevention of liver diseases. Areas of interest include development of reliable and practical means of diagnosis of liver diseases; biomarkers for disease activity and stage; noninvasive tests for inflammation, fibrosis and fat in the liver; and drugs, complementary and alternative modalities, biologics or molecular reagents for the therapy or prevention of liver diseases. The goal of this announcement is to enlist members of the small business research community in advancing means of diagnosis, treatment and prevention of liver disease and facilitate the goals outlined in the trans-NIH Action Plan for Liver Disease Research. Mechanism of Support. This FOA will utilize the STTR (R41/R42) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-095, that encourages applications under the Small Business Innovation Research (SBIR) (R43/R44) grant mechanisms. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received.

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