Pathophysiology of Bisphosphonates-associated Osteonecrosis of the Jaw (R21)

archived

-The National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), and the National Cancer Institute (NCI) invite Exploratory/Developmental (R21) grant applications for research projects focusing on basic and translational studies of osteonecrosis of the jaw (ONJ), an oral complication associated with bisphosphonate use. Projects should aim to identify and characterize the pathophysiological mechanisms that lead to impaired bone healing and the development of ONJ. -This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with two FOAs of identical scientific scope, PA-06-500 that solicits applications under the NIH Individual Research Project Grant (R01) mechanism, and PA-06-502 that solicits applications under the NIH Small Research Grant (R03) mechanism. -Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

High