PEP Packs: Postexposure Prophylaxis Packs for Immediate Access to HIV and Sexually Transmitted Infection Prevention

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The purpose of this notice of funding opportunity (NOFO) is to support an implementation research study. In this study, optimal strategies will be assessed for a postexposure prophylaxis (PEP) in pocket (PiP) approach for prevention of HIV and sexually transmitted infections (STIs) among gay, bisexual, and other men who have sex with men (MSM) and transgender women (TGW). The recipient will implement and evaluate a comprehensive strategy to integrate PEP packs as a component of existing PrEP and STI clinical services. PEP packs will include a supply of antiretroviral medication for nonoccupational PEP (nPEP), doxycycline for STI PEP (DoxyPEP), HIV and STI self-test kits, and instruction materials. Study clinics should be in communities with high rates of HIV diagnoses among disproportionately affected populations, especially Black and Hispanic MSM and TGW.