Preclinical validation of a novel immunogenic composition to stimulate innate immunity
Location: France
Source: EU Funding & Tenders Portal
Immunotherapy is a promising approach to treat cancer and infectious diseases, but innovative approaches are required. The cGAS-cGAMP-STING pathway can induce a potent immune response against viruses. It is also implicated in antitumoral immune responses that are effective. We have recently discovered that the small second messenger cGAMP can be packaged by viruses to stimulate immunity in target
- Status
- Closed
- Location
- France
- Updated
- 22 Jul 2026
- Source
- EU Funding & Tenders Portal
ConstructChat
Ask ConstructChat about Preclinical validation of a novel immunogenic composition to stimulate innate immunity
Pick a question to edit it, or write your own.
First answer free · no account
Project Information FAQ
Project Information
Participants
| Not available for this record. |
Status
Original status | ended |
Taiyo status | Closed |
Taiyo last update | 2026-07-22 |
Contact
| Not available for this record. |
Description
Description | Immunotherapy is a promising approach to treat cancer and infectious diseases, but innovative approaches are required. The cGAS-cGAMP-STING pathway can induce a potent immune response against viruses. It is also implicated in antitumoral immune responses that are effective. We have recently discovered that the small second messenger cGAMP can be packaged by viruses to stimulate immunity in target cells. We have developed methods to produce non-infectious virus-like particles containing cGAMP (cGAMP-VLPs) that strongly stimulate this innovative immune pathway. We will test the idea that cGAMP-VLPs are potent activators of anti-tumoral and anti-viral immunity. To reach this proof-of-concept, we propose pre-clinical development plan in translational mouse models. |
Location
Country | France |
Source
Source | EU Funding & Tenders Portal |
URL |
More Details
Record type | Project |
Article published date | 2026-01-15 |
Research
Free account
View all details
You are reading the public part. A free account opens the rest:
- Every detail on this project
- News and media coverage
- Technical research
Free account · no card · lands you back on this project
More infrastructure projects in France
- PaimpolBrehat Tidal Farm
- Saint Nazaire Wind Farm France
- ToulRosieres Solar Park
- Flamanville 3 Nuclear Power Plant Normandy
- DieppeLe Trport Offshore Wind Farm Normandy France
- Flamanville Nuclear Worlds Largest European Pressurised Reactor France
- Projet 17e - Porte Pouchet
- Projet 18e - Porte des Poissonniers