Programs of Excellence in Glycosciences (P01)

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Purpose. The National Heart, Lung, and Blood Institute (NHLBI) solicits applications to participate in the Programs of Excellence in Glycosciences (PEG).The goal of the PEG is to translate emerging discoveries in glycosciences into new diagnostics and clinical applications and to build research capacity. This program will create resources and a cadre of scientifically bilingual investigators fluent in glycan chemistry and biology that will sustain and advance the application of glycosciences to heart, lung, and blood research.To accomplish this goal, the initiative will support new partnerships to conduct multidisciplinary research, provide a glycosciences skills development core to nurture and develop new investigators, and establish a shared resources core to advance the application of glycosciences to heart, lung, and blood research. Mechanism of Support. This FOA will utilize the Program Project (P01) grant mechanism.An NHLBI P01 application requires a minimum of three interrelated research projects that focus a number of scientific disciplines on investigations of a complex biomedical theme or research question.Applications in response to this FOA should have a shared resources core to enhance research productivity and increase functional capacity in the glycosciences.Another key requirement of this program is to establish a glycosciences skills development core that would provide high-quality, specialized courses to scientists on the application of glycosciences to heart, lung, and blood research. Funds Available and Anticipated Number of Awards. The NHLBI intends to commit approximately $12 million total costs for FY 2011.It is anticipated that four to five P01 awards will be made through this FOA.

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