Rapid Translation of Epidemiological Findings into Interventions to Prevent Substance Use and Addiction (R61/R33 Clinical Trial Optional)

archived

The goal of this initiative is to address the structural incentives that limit translation from epidemiology into prevention science using a two-pronged approach. The phased R61/R33 mechanism will support innovative epidemiologic research using either primary data collection or analysis of existing data related to substance use and addiction in the R61 phase to provide the foundation for a targeted prevention intervention in the R33 phase. The R33 phase would apply the findings from the R61 phase to either a) adapt or target an existing intervention to increase effect size or reach a new population or b) develop a novel intervention to address a new prevention target. Applicants would be required to use an MPI/MPD structure so that there is a PI with relevant expertise to lead the different components of the project. The supplement mechanism will capitalize on bidirectional translational science wherein existing epidemiological projects can submit proposals to test prevention hypotheses as well as prevention interventions can submit proposals for additional epidemiological inquiry to help contextualize their findings.

High