Reducing Inequities in Cancer Outcomes through Community-Based Interventions on Social Determinants of Health

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The purpose of this NOFO is to conduct evaluation research to build an evidence base of innovative, community-based interventions across multiple domains of social determinants of health to reduce racial and ethnic disparities in cancer outcomes. Evaluation research is defined as the systematic application of public health research procedures for assessing the conceptualization, design, implementation, effectiveness and utility of public health interventions. This research would advance our understanding of what works, for whom and why. Component A: Primary Cancer Prevention – to conduct evaluation research on an innovative, multi-sector intervention to reduce cancer risk in one or more socially or economically disadvantaged populations. This research will examine the implementation, impact, and causal mechanisms of the intervention’s effect to reduce cancer risk at the population level. Component B: Cancer Screening – to conduct evaluation research on an innovative, multi-sector intervention to reduce inequities in the receipt of appropriate screening services (on-time initial screening, routine re-screening at recommended intervals, appropriate follow-up after inconclusive/incomplete screening) among one or more socially or economically disadvantaged populations. This research will generate knowledge about the implementation, impact, and causal mechanisms of the intervention’s effect on cancer screening outcomes. Component C: Health and Wellbeing of Cancer Survivors – to conduct evaluation research on an innovative, multi-sector intervention to address barriers to health and well-being among cancer survivors from one or more socially or economically disadvantaged populations. This research will generate knowledge about the implementation, impact, and causal mechanisms of the intervention’s effect on the health and wellbeing of cancer survivors. Applicants may apply for one Component (Component A or Component B or Component C).

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