Research on Interventions for Child Abuse and Neglect (R01)

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Purpose. This Funding Opportunity Announcement (FOA) solicits research project grant (R01) applications focused on conducting efficacy and effectiveness trials of child abuse and neglect interventions. Specifically, this FOA solicits grant applications that include various levels of interventions. For those interventions that need preliminary research, applicants should consider additional mechanisms, which are used to establish efficacy, including the R21 and R34, as appropriate. However, given the public health need for children and families who experience the negative effects of child abuse and neglect, interventions in which preliminary developmental/exploratory work has already been undertaken, and pilot studies, or in some cases efficacy trials, have demonstrated positive change are strongly encouraged for R01 grant applications under this FOA. Of particular interest is the development of large scale trials designed to target either or both the victims or perpetrators of child abuse and neglect, including preventive interventions. Child abuse and neglect is a complex public health issue likely caused by a myriad of factors, including individual-, family-, and community-level elements. Thus, a research program focused on understanding and addressing these problems must necessarily draw upon interdisciplinary theories and approaches. One of the goals of this FOA is to bring together multi-disciplinary and translational perspectives encompassing basic biomedical, behavioral and social science research in mental health, physical health, public health and prevention, alcohol and substance abuse, neurology, injury, trauma and child development, to advance our knowledge of child abuse and neglect. Only projects proposing rigorous scientific research designs will be considered; service demonstrations or other types of service programs are not eligible for funding under this FOA. Mechanism of Support. This FOA will use the NIH Research Project Grant (R01) award mechanism. Applications for Exploratory/Developmental Grant (R21) and NIMH Clinical Exploratory/Developmental Research Grant (R34) are also sought for appropriate efficacy, exploratory, and treatment development studies. Applicants for the R21 and R34 award mechanisms should respond to the following FOAs for these mechanisms (NIH R21-PA-06-181; and the NIMH R34-PAR-06-248). Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and cost of the applications received. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Eligible Agencies of the Federal government; Faith-based or community-based organizations. Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct. Renewals and Resubmissions. Applications can be renewed by competing for additional project periods. Applicants may submit a resubmission application, but such application must include an Introduction addressing the previous peer review critique (Summary Statement). Number of PDs/PIs. More than one PD/PI, or multiple PDs/PIs, may be designated on the application.

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