Research on Malignancies in the Context of HIV/AIDS (R21)

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This funding opportunity announcement (FOA) encourages Research Project Grant (R21) applications from institutions/organizations that propose to continue advancing our understanding of the risks, development, progression, diagnosis, and treatment of malignancies observed in individuals with an underlying Human Immunodeficiency (HIV) infection or Acquired Immune Deficiency Syndrome (AIDS). The NCI and NIDCR encourage research in areas such as the study of the etiologic factors, cofactors, immunopathogenesis, diagnosis, and consequences of both non-AIDS defining and AIDS-defining malignancies in diverse populations. This FOA encourages research efforts that will (i) provide information on the clinical outcomes of such cancers in the HIV-infected population and (ii) identify specific contributions resulting from HIV infection and its potential interaction with other pathogens for the development and pathogenesis of these cancers. Ultimately, such efforts could inform screening approaches and therapies targeted to the HIV-infected population.

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