Rigorous Evaluation of Primary and Secondary Overdose Prevention Activities Among Populations Disproportionately Affected by Overdose

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This NOFO funds research focused on people experiencing disproportionate burden of drug overdose, those who are at greater risk of exposure to drug use, or those experiencing adverse drug use outcomes related to social determinants of health. Your research should rigorously evaluate either primary or secondary prevention strategies for reducing rates of nonfatal overdose, fatal overdose, and/or substance use disorders involving federally illegal drugs or misuse of prescription medications, drug use, or initiation of drug use, particularly among youth.