Symptom Interactions in Cancer and Immune Disorders (R01)

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-Purpose. This funding opportunity announcement (FOA) issued by the National Institute of Nursing Research (NINR), National Cancer Institute (NCI), National Center on Complementary and Alternative Medicine (NCCAM), National Institute on Aging (NIA), National Institutes of Health (NIH), solicits grant applications from applicant organizations that propose to (a) identify and assess biobehavioral interactions among two or more related and co-occurring symptoms; (b) characterize mechanisms and pathways underlying the symptom interactions; (c) elucidate the level of interaction necessary for categorization as a symptom cluster; and/or (d) design and test interventions targeted to interacting or clustered symptoms that are hypothesized to lead to beneficial patient outcomes. A rationale for the choice of symptoms is needed, not just co-occurrence of two or more symptoms, and they must be associated with a target disease or syndrome or its treatment. Studies at any point in the disease trajectory, or during the survivorship period are encouraged. -Mechanism of Support. This FOA will utilize the R01 grant mechanism and runs in parallel with a FOA of identical scientific scope, PA-08-122, that encourages applications under the R21 grant mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

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