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Understanding the Effects of ApoE2 on the Interaction between Aging and Alzheimers Disease (R01)

Sector: Government • Location: United States of America

Source: Grants.gov

Project
Archived

This FOA invites applications on descriptive, basic and translational studies of APOE2 to delineate the functional effects of ApoE2 on healthy aging of the brain and other tissues. The primary focus is on the APOE2Aging-AD" relationship and the mechanistic effects of the protective variant on aging and potential interaction/cross talk between tissues in the aging process and AD. These studies are

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The project “Understanding the Effects of ApoE2 on the Interaction between Aging and Alzheimers Disease (R01)” is an infrastructure initiative in the Government sector, located in United States of America. Taiyo aggregates data on it from Grants.gov.

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archived

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Description

Description

This FOA invites applications on descriptive, basic and translational studies of APOE2 to delineate the functional effects of ApoE2 on healthy aging of the brain and other tissues. The primary focus is on the APOE2Aging-AD" relationship and the mechanistic effects of the protective variant on aging and potential interaction/cross talk between tissues in the aging process and AD. These studies are expected to generate new mechanistic insights that involve brain and/or other organs and assist in the identification of potential prognostic and diagnostic markers and therapeutic targets for AD and other age-related cognitive disorders. Eventually, the findings from these studies could lead to translational research opportunities not only to prevent or delay the onset of AD, but also to protect against multiple age-related conditions.

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High

Data quality score

100%

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