Upgrade automatizace krystalizace

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Předmětem plnění veřejné zakázky je dodávka, instalace a zprovoznění upgrade automatizace krystalizace spolu se službami, jež se vztahují k předmětu dodávky dle specifikace uvedené v Návrhu kupní smlouvy. Jedná se o upgrade: i) Krystalizačního robota NT8 výrobce Formulatrix, Inc. (HW) a ii) SW Formulatrix prostředí (základními složkami jsou RockImager, RockMaker a RockMakerWeb), který se týká přístrojů výrobce Formulatrix, Inc.: Krystalizační hotel RI1000 (vč. SW RockImager, RockMaker a RockMakerWeb a tiskárny čárových kódů) (pořizovací cena: 3.955.120,- Kč bez DPH, r. 2015; navýšení kapacity hotelu v r. 2019 v hodnotě 82 006 EUR bez DPH) SONICC (pořizovací cena: 678.808 EUR, r. 2021) Krystalizační hotel RI182 (pořizovací cena 249 785 EUR, r. 2020) Krystalizační robot NT8 (pořizovací cena: 106 392 EUR bez DPH, r. 2019) Absolutní (minimální) technické požadavky / Absolute (minimum) technical requirements: Upgrade of Nanodispenzer for protein crystallization experiments, • Nanodispenzer must have an automatic calibration option, which can calibrate the system without the necessity to use the manual mode. • Nanodispenser must be able to dispense nanoliter drops with range of at least 50-200 nl. • Nanodispenser must be able to do the sitting drop and hanging drop crystallization experiments, including 96-well plates of SBS format and 24-well plates • Must include Plate Copy option, to be able to dispense/pipette well solutions from at least 96-well deep well blocks to 96-well crystallization plates • Must be able to dispense lipidic cubic phase experiments • The dispenser must be able to control the humidity around the small drops to avoid the evaporation. Must be able to set relative humidity from ambient up to 95 % and actively keep that level. • Dispenser must be able to re-use tips when user choses to do so, but also be able to use disposable tips to avoid contamination in certain pipetting experiment. • The upgraded plate copy option must avoid the need to lubricate the large-volume pipetting head o-rings; • Must run on Windows 11 Upgrade to the Formulatrix Environment/Software Upgrade • All new versions of software must be compatible with the existing crystallography equipment including RI1000 with SONICC, RI182, the barcode printer and the upgraded version of NT8. • Upgrade will allow remote access from various operating systems -at least Windows, Mac, Linux (not including mobile phones) • Upgrade to browser-based software, meaning the software is not reliant on a specific Windows version. The possibility to use the on-site application will be kept as well. • Addition of crystallisation autoscoring models including MARCO, Sherlock 1 and Sherlock 2 • Updated search and filter to allow quick comparison of drop images to better understand crystal growth parameters • Enhanced crystal tracking for synchrotron trips allowing for reusability of dewars and pucks in different trips • Full installation must be provided • Full training on new software must be included • Must run on Windows 11 • Rock Maker Web upgrade must be also included, and must continue to provide remote user access at least as per the current software configuration

Laboratory, optical and precision equipments (excl. glasses), IT services: consulting, software development, Internet and support

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